Transplantation MRes

The Transplantation MRes enables you to experience an internationally competitive research area, predominantly in academia but also potentially in industry. The MRes can be taken either as a stand-alone qualification or provide an entry route onto a PhD or MD.<br/><br/>**Applications for this course are now open**<br/>You can now apply for September 2021 entry using our postgraduate application portal.<br/><br/>The course is designed for graduates with a BSc in the life sciences and is also suitable for graduates from other science disciplines and intercalating and fully qualified MBBS or BDS students.<br/><br/>There is a taught component with subject-specific content in the area of Transplantation. Subject-based modules provide a broad exposure to diverse aspects of transplantation, from clinical concepts to cutting edge scientific development. There will be a unique opportunity to gain insights into the speciality of transplantation sciences in the context of transplantation of haematopoietic stem cells, corneal/limbal stem cells and a variety of solid organs.<br/><br/>Modules aim to:<br/>•provide sound understanding of the scientific basis underlying the therapeutic benefits and adverse effects of clinical transplants<br/>•highlight the research areas where applications of immunology and cell biology can improve transplant outcome and patient wellbeing<br/>•provide a view of bench to bedside translational links between scientific research and clinical practice<br/><br/>The course emphasises the clinical practice driven research, which prepares students for a future career in either medical practice or broad biomedical research. <br/><br/>Main topics covered:<br/>•transplantation immunology related to cellular and molecular basis of allogeneic immune responses, tolerance, immunosuppression<br/>•the genetic and molecular basis of HLA system, non-HLA immunogenetics, histocompatibility, impact of HLA matching in choice of donor / transplant outcome<br/>•transplantation pathology related to graft-versus-host disease following haematopoietic stem cell transplant, rejection following solid organ transplant, tissue damage and loss of graft function<br/>•manipulation of haematopoietic stem cells for clinical use<br/>•development of novel therapeutic strategies to aid improvement of clinical transplant outcome<br/><br/>It has the flexibility for you to develop your own bespoke course by choosing additional, complementary modules from a wide selection. You will also undertake training in general research principles and other professional and key skills.<br/><br/>The research project comprises the major element of the course. This project will involve 24 weeks’ carrying out research in the area of transplantation under the supervision of an expert academic researcher in the field.<br/><br/>This MRes is closely linked to a suite of MRes courses that you may also be interested in:<br/>•Ageing and Health<br/>•Animal Behaviour<br/>•Biotechnology and Business Enterprise<br/>•Cancer<br/>•Cardiovascular Science in Health and Disease<br/>•Cell Signalling in Health and Disease<br/>•Diabetes<br/>•Epidemiology<br/>•Evolution and Human Behaviour<br/>•Immunobiology<br/>•Medical Genetics<br/>•Medical Molecular Biosciences<br/>•Medical Technology Innovation<br/>•Mitochondrial Biology and Medicine<br/>•Molecular Microbiology<br/>•Musculoskeletal Ageing (CIMA)<br/>•Neuromuscular Diseases<br/>•Neuroscience<br/>•Stem Cells and Regenerative Medicine<br/>•Systems Biology<br/>•Toxicology<br/>•Translational Medicine and Therapeutics<br/><br/>Faculty of Medical Sciences Graduate School:<br/>Our Graduate School is dedicated to providing you with information, support and advice throughout your research degree studies. We can help and advise you on a variety of queries relating to your studies, funding or welfare.<br/><br/>You will make an on-going assessment of your own development and training needs through personal development planning (PDP) in the ePortfolio system. Our organised external events and development programme have been mapped against the Vitae Researcher Development Framework to help you identify how best to meet your training and development needs.